Parkinson’s Disease

Treating Advanced Parkinson’s

Patients with Parkinson’s disease (PD) have essentially the same life expectancy as people without PD. This means that patients, especially those who are diagnosed early in life, will require treatment for a very long period of time (30 years and more). In this video, Dr. Stern explains 2 more invasive approaches that allow the patient to improve their symptoms while also reducing their medications. In particular, Dr. Stern discusses the use of DBS and DUOPA, which delivers a gel formulation of levodopa directly into the small intestine.

Treating Advanced Parkinson’s

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Patient questions
  • Is it time for me to think about more advanced treatments such as Duopa or deep brain stimulation (DBS)?
  • Am I a candidate for DBS? If YES, what can I expect from DBS? What are my risks?
  • Assuming I will have DBS, what are the next steps? How long will the device last? What about the batteries? Can we adjust the device once it is implanted?
  • Am I a candidate for Duopa? If YES, what can I expect from Duopa? What are my risks?
  • Assuming I will have surgery for Duopa, what are the next steps? Does the device need to be filled up again? Does it run out of battery?
  • Which form of advanced treatment would you recommend to me at this time? Points you might want to raise during the discussion with your doctor:
    • Any incidence of falling / other safety risk resulting from your imbalances
    • Updates on non-motor symptoms
Approach to Non-Motor
Symptoms
What Can I Expect in
the Future?